3 year old child, A.C. staying at Nalasopara, came to Homoeocare for the treatment of developmental delay and convulsions since age of 3 month. Child get 4 to 5 episodes of tonic and clonic spasm a day and each episode last for 4-5minutes. She was not responding to her name, lacking in understanding and at age of 3 year she stood with support.
EEG report showed Right hemisphere burst; multifocal epileptiform activity present over both hemispheres. MRI of brain showed Agenesis of corpus callosum with severe hypomyelination, accompanied with cortical dysplasia. BERA showed bilateral mild hearing loss.
She was diagnosed as Aicardi syndrome. It is diagnosed by triad of partial or complete absence of corpus callosum, Chorioretinal lacunae and Infantile spasms. Corpus callosum allows normal flow of information between right and left hemisphere of brain. Agenesis of corpus callosum leads to frequent seizures, vision and hearing impairment, developmental delay, poor muscle tone and coordination, learning difficulty, abstract thinking, attention deficit disorder. In Chorioretinal lacunae there is punched out lesion in pigmented retina. The onset of infantile spasm is mostly seen around the age of 3month due to closure of final neural synapses during the development of brain. Aicardi syndrome is genetic disorder , thought to be caused by mutation specifically occurs on X Chromosome as it is mostly found in girls and smaller number in boys as klinefilter syndrome.
After homoeopathic treatment at Homoeocare her understanding skill started improving and within 1year frequency of convulsion gradually reduced to once a month. BERA report shows no abnormality.
Post By: Dr-Admin